Each month, we compile and present a comprehensive up-to-date list of recently started clinical trials to keep you informed of the latest advancements and research in the medical field. To be the first to know about new clinical trials Register Now for free

The below are the clinical trials posted for the first time in May 2024.

Phase 4:

  1. Effect of Proactive Therapeutic Drug Monitoring on Maintenance of Sustained Disease Control in Adults With Rheumatoid Arthritis on a Subcutaneous TNF Inhibitor: The Rheumatoid Arthritis Therapeutic DRUg Monitoring Trial (RA-DRUM)
  2. Effects of Growth Hormone Therapy on Metabolic Function in Fatty Liver Post-Pituitary Adenoma Surgery
  3. Efficacy of Human Papillomavirus (HPV) Vaccination to Prevent Infection Among Women Living With HIV.
  4. Role of TXA in Patients Undergoing Breast Free Flap Reconstruction
  5. Effect of Alpha Lipoic Acid on Chemotherapy Induced Neurological Changes in Breast Cancer Patients
  6. Study Evaluating Safety, Tolerability, and Metabolism of Niraparib
  7. Efficacy and Safety of Prunella Oral Liquid in the Treatment of Thyroid Nodules
  8. Deeper Intubation Make Effects on Cervical Esophageal ESD
  9. Clinical Study of Asciminib in Previously Treated Indian Patients With Ph+ CML-CP Without T315I Mutation and in Patients With Ph+ CML-CP With T315I Mutation
  10. The Preoperative Administration of ICG Improves Tumor Detection in Patients Undergoing Minimally Invasive Hepatic Resection Guided by Conventional Intraoperative Ultrasound.
  11. Safety and Modulation of Adaptive Immunity by IscadorΒ® Qu Viscum Album Extract in Patients With Advanced, Recurrent or Metastatic Cancers Treated With Immune Checkpoint Inhibitors
  12. Lenvatinib and Adebrelimab Combined With GEMOX in the Perioperative Treatment of Potentially Resectable Intrahepatic Cholangiocarcinoma

Phase 3:

  1. SHR-A1921 for Injection in Patients With Platinum-Resistant Recurrent Epithelial Ovarian Cancer
  2. Lomustine in Addition to Standard of Care in Patients With MGMT Methylated Glioblastoma
  3. JAB-21822 Combined With JAB-3312 Compared SOC in the First Line for Treatment of Advanced Non-small Cell Lung Cancer With KRAS p.G12C Mutation
  4. Multicenter Clinical Trial on the Effectiveness and Safety of Instillation of BCG and Alternative BCG Protocols for Intermediate and High-risk Non-muscle Invasive Bladder Cancer
  5. Liposomal Bupivacaine vs Ropivacaine for TAPBs
  6. Safety, Efficacy and Pharmacokinetic Behavior of Leuprolide Injectable Emulsion for Premenopausal Breast Cancer Subjects.
  7. A Phase 3, Randomized, Open-label, Controlled Study Comparing the Efficacy and Safety of Zanidatamab to Trastuzumab, Each in Combination With Physician's Choice Chemotherapy, for the Treatment of Participants With Metastatic HER2-positive Breast Cancer
  8. A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)
  9. Platinum and Taxane Chemo in Met Castration Resistant Prostate Cancer Patients With Alterations in DNA Damage Response Genes
  10. Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR
  11. Phase III Study of AK112 for NSCLC Patients
  12. De-scalation or swItch of Treatment According to Circulating tuMOr DNA Variation After 2 Cycles of Doublet Chemotherapy Plus Targeted Agent in Metastatic Unresectable Colorectal Cancer
  13. Efficacy and Safety of TPC+Apatinib+Camrelizumab vs GP+ Camrelizumab for High-Risk Nasopharyngeal Carcinoma: A Phase 3 Trial
  14. IMPACT-AML: Randomized Pragmatic Clinical Trial for Relapsed or Refractory AML
  15. Wisconsin Ginseng for Decreasing Cancer Related Fatigue
  16. PM8002 or Placebo Plus Nab-Paclitaxel as First-line Treatment in Inoperable Locally Advanced/Metastatic Triple-negative Breast Cancer
  17. ADT and SBRT vs SBRT Alone for Unfavorable Intermediate Risk Prostate Cancer
  18. Evaluation Contact X-ray Brachytherapy for Rectal Preservation in Intermediate Substage Rectal Adenocarcinoma
  19. Apatinib Combined With cdk4/6i in First-line Treatment for HR+/HER2- SNF4 Subtype Breast Cancer
  20. Postoperative Adjuvant Chemotherapy for Thymic Cancer (FUSCC-Thymic 3)
  21. An Open-label Extension Study to Evaluate Subcutaneous Zilucoplan in Pediatric Participants With Generalized Myasthenia Gravis
  22. A Study of SKB264 in Combination With Pembrolizumab Versus Pembrolizumab in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
  23. The Efficacy and Safety of Nelarabine Injection in Patients With T-lymphoblastic Leukemia and T-lymphoblastic Lymphoma
  24. Improvement of Quality of Life Through Supportive Treatments for Hormone Therapy - Related Symptoms in Women With Early Breast Cancer
  25. A Study to Confirm if Fezolinetant Helps Reduce Hot Flashes in Women With Breast Cancer Who Are Having Hormone Therapy
  26. Myoinositol, L-arginine and Chromium With Letrozole for Ovulation Induction in Polycystic Ovarian Syndrome Patients
  27. A Study to Investigate the Efficacy and Safety of Dato-DXd With or Without Osimertinib Compared With Platinum Based Doublet Chemotherapy in Participants With EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer
  28. Photodynamic Diagnosis for Malignant Brain Glioma With 5-Aminolevulinic Acid(5-ALA)
  29. PH Weighted Chemical Exchange Saturation Transfer MRI-Based Surgical Resection to Improve Survival in Patients With Glioblastoma
  30. Short Versus Long-term Levetiracetam in Brain Tumors
  31. Treatment of Malignant Ascites Caused by Advanced Epithelial Solid Tumors With M701 Bispecific Antibody
  32. Pharmacokinetic Similarity Between ABP 234 and KeytrudaΒ® (Pembrolizumab)
  33. A Study to Evaluate the Risk of Tumor Lysis Syndrome (TLS) in Adult Participants Receiving Oral Venetoclax in Combination With Intravenously Infused Obinutuzumab or Oral Acalabrutinib for Previously Untreated Chronic Lymphocytic Leukemia (CLL)
  34. Clinical Study of 18F-Alfatide Injection PET/CT
  35. A Phase 3 Registrational Study of Olverembatinib (HQP1351) in Patients With CML
  36. An Extension Study for Patients Previously Enrolled in Studies With Pelabresib
  37. Adjuvant Therapy With Letrozole in Induction of Ovulation With Polycystic Ovarian Syndrome
  38. Safety and Efficacy of Pembrolizumab in Combination With FLOT About Gastroesophageal Junction Cancer:
  39. A Study of SHR-A1811 in First-line Treatment of Patients With Advanced or Metastatic Non-small Cell Lung Cancer With HER2 Mutations
  40. A Study Comparing Anitocabtagene Autoleucel to Standard of Care Therapy in Participants With Relapsed/ Refractory Multiple Myeloma
  41. The Trial of SHR6508 in Secondary Hyperparathyroidism
  42. Clinical Study on the Effect of Removal of Porphyromonas Gingivalis on Prognosis of Esophageal Cancer After Radical Surgery
  43. Effect of ALA Combined With Letrozole on Polycystic Ovary Syndrome Clinical Outcome in Infertile Females
  44. Clinical Trial Protocol: Randomized Placebo-Controlled Pilot Study of GcMAF (Soloways TM) in Patients With Metastatic Breast Cancer
  45. Adjuvant Chemoradiotherapy Versus Chemotherapy for Pancreatic Cancer (ADJUPANC)
  46. Neoadjuvant Therapy of SBRT Sequencial With Toripalimab and Chemotherapy in Resectable Stage II-III NSCLC Patients(neoR-TORCH)

Phase 2-3:

  1. Nimotuzumab Combined With GX as Postoperative Adjuvant Therapy in Pancreatic Cancer
  2. A Clinical Study to Evaluate the Safety and Efficacy of Lutetium[177Lu] Oxodotreotide Injection in Patients With Advanced Neuroendocrine Neoplasms
  3. A Study of HS-20117 Combined With Aumolertinib in Participants With Advanced Non-Squamous Non-Small Cell Lung Cancer
  4. Fruquintinib With or Without HAI-FOLFOX for Refractory Colorectal Cancer
  5. FPI-2265 (225Ac-PSMA-I&T) for Patients With PSMA-Positive Metastatic Castration-Resistant Prostate Cancer (mCRPC)
  6. Smoking Cessation CM for Veterans With or at Risk for Cancer
  7. Neoadjuvant Fruquintinib Plus Tislelizumab Combined With mCapeOX Versus CapeOX for Mid-high pMMR/MSS Locally Advanced Rectal Cancer
  8. A Clinical Study to Evaluate Safety, Tolerability and Pharmacokinetics of SV001 in Chinese Healthy Adult Volunteers.

Phase 2:

  1. Phase II Study of REPotrectinib With or Without Fulvestrant in Patients With Hormone Receptor-positive Human Epidermal Growth Factor 2-negative Metastatic Invasive LObular Carcinoma Who Received a Prior Endocrine Therapy in Combination With Cyclin-dependent Kinase 4 and 6 Inhibitor (REPLOT Trial)
  2. High-dose Chemotherapy as Second-line Drug Therapy for Relapsed Germ Cell Tumors
  3. Mitoxantrone Hydrochloride Liposome Injection, Cytarabine Combined With Venetoclax in the Treatment of R/R AML
  4. CMOEP in the Treatment of Untreated Peripheral T-cell Lymphoma
  5. A Study of SBRT Combined With Puterizumab in Intrapulmonary Metastasis From NSCLC
  6. A Prospective Study: Sintilimab and R-CHOP in PMBCL Treatment
  7. The Efficacy of Bevacizumab and Serplulimab Combined With Recombinant Mutant HumanTumor Necrosis Factor(rmhTNF-NC) in the Treatment of Malignant Ascites
  8. Phase II Trial of Ubamatamab Alone or in Combination With Cemiplimab in MUC16-Expressing SMARCB1-Deficient Malignancies
  9. Multimodal Rehabilitation on Gastric Adenocarcinoma Patients Following Radical D2 Gastrectomy
  10. Osimertinib and Etoposide as First-Line Treatment in Osimertinib-Resistant Advanced EGFR-Mutant NSCLC
  11. Neoadjuvant Pembrolizumab, Carboplatin and Paclitaxel in Triple-negative Breast Cancer
  12. The Efficacy and Safety of Cadonilimab (AK104) as Induction and Consolidation Therapy for Locally Advanced/Unresectable NSCLC Patients Receiving Concurrent Chemoradiotherapy
  13. Obinutuzumab Combined With Bendamustine in the Treatment of Mature B-cell Lymphoma
  14. Vemurafenib and Cobimetinib for the Treatment of Patients With High Risk Differentiated Thyroid Carcinoma With BRAFV600E Mutation
  15. Efficacy and Safety of Modified Si Jun Zi Tang in Perioperative NSCLC Treatment
  16. Using CircuLating Tumor DNA to Risk Adapt Post-Operative Therapy for HPV-associated Oropharyngeal Cancer
  17. Rectus Sheath Block With Liposomal Bupivacaine Versus Thoracic Epidural Analgesia for Pain Control Following Pancreatoduodenectomy
  18. Chidamide Combined With Sintilimab and Bevacizumab for the First-line Treatment of Advanced Liver Cancer
  19. Adaptive Moderately Hypofractionated Post Operative Radiotherapy
  20. An Investigational Scan (Ga-68 PSMA-11 PET/CT) for Detection of Disease Recurrence or Progression in Patients With Glioma
  21. RC48 Treatment for Platinum Sensitive Recurrent Ovarian Cancer With HER2 Expression
  22. Evaluating Nimotuzumab in Combination With AG Regimen for Pancreatic Cancer With Liver Metastases : A Prospective, Single-Arm, Phase II Study
  23. Topical Ruxolitinib Evaluation in Immune-related Lichenoid Skin-Toxicities
  24. KRAS-Targeted Vaccine Combined With Balstilimab and Botensilimab for Patients With Stage IV MMR-p Colorectal Cancer and Pancreatic Ductal Cancer
  25. To Explore the Efficacy of Hypofractionated Radiotherapy Followed by AG Regimen Chemotherapy Plus Camrelizumab Immunotherapy as Neoadjuvant Therapy for Locally Advanced Pancreatic Cancer
  26. Clinical Study of Irinotecan Hydrochloride Liposome Combined With Capecitabine for Second-line Treatment in Patients With Advanced or Metastatic Biliary Tract Carcinoma
  27. Camrelizumab Plus Fluzoparib for TP-53 Mutated Endometrial Cancer
  28. Darolutamide in Metastatic Castration-Resistant Prostate Cancer (mCRPC)
  29. A UGT1A1 Genotype-Directed Study of Belinostat Pharmacokinetics and Toxicity
  30. High-dose Furmonertinib in the Treatment in Patients With Advanced, Metastatic NSCLC With Progressed After First- or Second-line Treatment With Osimertinib
  31. A Study of BL-B01D1 + PD-1 in Patients With Locally Advanced or Metastatic Urothelial Carcinoma
  32. SHR-A1811 in Combination With Adebrelimab for the Treatment of HER2 Low-expressing Metastatic Breast Cancer
  33. A Study of Cadonilimab(AK104)Combined With Standard Treatment for Function Preservation in Urinary System Tumors
  34. High Intensity Focused Ultrasound in Prostate Cancer
  35. Evaluation of the Possible Safety and Efficacy of Dapagliflozin in the Prophylaxis of Doxorubicin-Induced Cardiotoxicity
  36. CBT-I in Primary Brain Tumor Patients: Phase IIc Randomized Feasibility Pilot Trial
  37. Intensive Cholesterol-Lowering and CD8+ T Cells in Prostate Cancer
  38. Testing BVD-523FB (Ulixertinib) as Potentially Targeted Treatment in Cancers With Genetic Changes (MATCH - Subprotocol Z1L)
  39. Study of Cadonilimab Combined With Chemotherapy in Recurrent / Refractory Pleural Mesothelioma
  40. MRD-Directed Consolidation With Epcor-only or Epcor-R2 Post Anti-CD19 CAR TCell Therapy for Large B-Cell Lymphoma
  41. Safety and Preliminary Effectiveness of BNT327, an Investigational Therapy for Breast Cancer, When Given in Combination With Chemotherapy
  42. Gemcitabine, Cisplatin and Nab-Paclitaxel as Neoadjuvant Treatment for Patients With Resectable or Borderline Resectable Pancreatic Cancer
  43. Nimotuzumab Concurrent With Chemoradiotherapy for Esophageal Cancer Patients
  44. Effectiveness and Performance of an Optical Biopsy Technology for Esophageal Cancer in Brazil and the United States
  45. Serplulimab Plus Chemoradiotherapy for Stage III-IVA Cervical Cancer
  46. A Phase II Clinical Study of Cadonilimab in Treatment-naΓ―ve or Relapsed Extensive Small Cell Lung Cancer
  47. Adebrelimab Plus Apatinib and Etoposide for the Treatment of HER2-Negative Breast Cancer Brain Metastasis
  48. Induction Chemoimmunotherapy Combined With Chemoradiotherapy in Esophageal Cancer
  49. Central-boost Ablative Radiation Therapy for Solid Tumors (CBART)
  50. Short-course Radiotherapy or Long-course Chemoradiation Followed by mFOLFOXIRI Consolidation Chemotherapy for Organ Preservation in Low Rectal Cancer
  51. The Effect of Probiotics ATG-F4 in Cancer Patients
  52. Sintilimab Plus Bevacizumab and SIRT for Intermediate-advanced HCC
  53. Sequential Tegafur-gimeracil-oteracil Potassium Capsule (s-1) and Serplulimab Following Concurrent Chemoradiotherapy for Esophageal Squamous Cell Carcinoma
  54. A Study to Evaluate the Efficacy of ALMB-0168 in Solid Tumor Patients With Bone Metastatic Whose Prior Standard Treatment Have Failed
  55. Use of Bleomycin in the Sclerotherapy of Lymphatic Malformations for Pediatric Patients
  56. Study of The Second-line Treatment of Advanced Gastric / Gastroesophageal Junction Adenocarcinoma With Cadonilimab and Fruquintinib Combined With Paclitaxel-albumin
  57. Nimotuzumab Combined With ICIs for the Treatment of Advanced Liver Cancer After First Line Treatment Failure
  58. Tuvusertib Combined With Niraparib or Lartesertib in Participants With Epithelial Ovarian Cancer (DDRiver EOC 302)
  59. 177Lu-DOTATATE Modified Delivery Based on Individualized Dosimetry
  60. A Study to Evaluate the Efficacy and Safety of Golcadomide in Combination With Rituximab in Participants With Newly Diagnosed Advanced Stage Follicular Lymphoma
  61. The Effect of Increasing Dialysate Calcium on T50 in Subjects With Secondary Hyperparathyroidism and ESKD
  62. Exploration of Therapeutic Strategies for NeoRAS Wild-type Metastatic Colorectal Cancer Based on Circulating Tumor DNA
  63. Ulixertinib in People With Histiocytic Neoplasms
  64. Cadonilimab Plus Chemotherapy as First-line Treatment for PD-L1 Negative NSCLC
  65. Neoadjuvant Tebentafusp for Uveal Melanoma
  66. An Investigational Scan (89Zr-DFO-GmAb PET/CT) Compared to Contrast-Enhanced CT for the Detection of Recurrent Clear Cell Renal Cell Cancer After Surgery Comparing Carbonic Anhydrase IX (CAIX) PET CT to Conventional PET CT for Post-Op Staging in Kidney Cancer
  67. A Value-Driven Study on Reducing Immune Checkpoint Inhibitor Dosing Frequency in Advanced Cancers
  68. Maintenance Durvalumab (MEDI4736) and Olaparib (AZD2281) After Standard 1st Line Treatment (Carboplatin/Cisplatin, Etoposide, Durvalumab) in HRD Positive Extensive Disease (ED) Small-cell Lung Cancer (SCLC)
  69. BRE-10: Biomarker Optimization of Neoadjuvant Therapy in Breast Cancer
  70. A Trial to Study the Safety and Efficacy of SM-020 Gel 1.0% in Subjects With Seborrheic Keratoses and Non-Melanoma Skin Cancers
  71. VMAC+DLI Treatment of Patients With Relapse of AML After Allo-HSCT
  72. Bladder Preservation for Patients With Muscle Invasive Bladder Cancer (MIBC) With Variant Histology
  73. NALIRI-XELOX+AK104 for First-line Treatment of Advanced PDAC
  74. Study of Fingolimod
  75. DapagliFLOzin in Renal AL Amyloidosis (FLORAL)
  76. Aromatherapy in the Treatment of Early Breast Cancer
  77. Nimotuzumab Plus NALIRIFOX in Locally Advanced Pancreatic Cancer
  78. A Study of Avutometinib, Defactinib, and Letrozole in People With Low-Grade Serous Ovarian Cancer
  79. Testing Copanlisib as Potentially Targeting Treatment in Cancers With PTEN Expression (MATCH - Subprotocol Z1H)
  80. Adjuvant Treatment With Serplulimab,Trastuzumab and SOX in the HER-2 Positive GC/GEJC
  81. Tamoxifen and Pegylated Liposomal Doxorubicin for the Treatment of Patients With Metastatic or Inoperable, Locally Advanced Triple Negative Breast Cancer
  82. Study of Magnetic Resonance Image and Computed Tomography-Guided Stereotactic Body Radiation Therapy for Abdominopelvic Sarcomas (MARS Trial)
  83. A Study of B013 in Combination With Paclitaxel in Patients With Platinum-resistant Recurrent Ovarian Cancer.
  84. A Study of Paclitaxel Combined With Apatinib and Adebrelimab in Gastric/Gastroesophageal Junction Adenocarcinoma
  85. Precision Medicine in Action: Phase II Trial of Response Adaptive Ablative Pre-operative SPBI (RAPS) and Non-operative Sentinel Lymph Node Biopsy in Patients With Early-stage ER+ Breast Cancer: RAPS Trial
  86. FOLFOX Chemotherapy Plus Fruquintinib and Sintilimab After First-line Treatment in Unresectable Hepatocellular Carcinoma
  87. Regorafenib in Combination With Multimodal Metronomic Chemotherapy for Chemo-resistant Metastatic Colorectal Cancers
  88. Neoadjuvant Prolgolimab Monotherapy in Locally Advanced MMR-deficient Colorectal Cancer
  89. Study of Treatment With Sacituzumab and Zimberelimab for Patients With Lung Cancer Confined to the Chest and Previously Operated on Who Were Not Disease-free.
  90. Onvansertib in Combination With Gemcitabine and Nab-paclitaxel for the Treatment of Patients With Locally-advanced, Unresectable, or Metastatic Pancreatic Ductal Adenocarcinoma
  91. Durvalumab With Carboplatin and Etoposide Chemotherapy in Pulmonary Large-cell Neuroendocrine Carcinoma (LCNEC)
  92. Hetrombopag for the Thrombocytopenia Induced by Concurrent Chemoradiotherapy
  93. Phase II Study of Post-Transplant Low-Dose Inotuzumab Ozogamicin to Prevent Relapse of Acute Lymphoblastic Leukemia
  94. PD-L1 Inhibitor Combined With Apatinib as First-line Maintenance Treatment for Extensive-stage Small Cell Lung Cancer
  95. Neoadjuvant PD-1 Inhibitor and EGFR Inhibitor in Locally Advanced Cutaneous Squamous Cell Carcinoma
  96. Sacituzumab Govitecan and Bevacizumab for NSCLC Brain Metastases
  97. Propranolol for the Treatment of Kaposi Sarcoma in Adults
  98. Sequential AG and mFOLFOX Combined With Serplulimab Injection and Bevacizumab Injection in Untreated Advanced Pancreatic Cancer
  99. Predicting Esophageal Cancer Borders Using PET-Imaging
  100. Toripalimab for High-risk Locally Advanced Cervical Cancer
  101. A Study of BL-B01D1+PD-1 Monoclonal Antibody in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma and Other Solid Tumors
  102. FIRST-NEC (GFPC 01-2022) - Combination of Durvalumab With Etoposide and Platinum
  103. A Phase II Study Evaluating an Organ Preservation Strategy Using Immune Checkpoint Blockade for Participants With Primary Colorectal or Gastroesophageal Cancer
  104. Blinatumomab Maintenance After Allo-HSCT
  105. Neoadjuvant Comprehensive Treatment for Unresectable Esophageal Cancer
  106. QL1706 Plus Chemotherapy as Neoadjuvant Therapy in Early High-Risk ER+/HER2- Breast Cancer
  107. SBRT, Chemotherapy, and AK112 Neoadjuvant Therapy for Luminal-type Breast Cancer
  109. Study of Belzutifan (MK-6482) Plus Fulvestrant for ER+/HER2- Metastatic Breast Cancer (MK-6482-029/LITESPARK-029)
  110. Study of Avelumab and Tuvusertib in Participants With Advanced Urothelial Cancer That Has Progressed on Prior Anti-PD-(L)1 Therapy (JAVELIN DDRiver Bladder)
  111. Efficacy and Safety of HAIC in Combination With TQB2868 and Ramucirumab for Second-line Treatment of Advanced Hepatocellular Carcinoma
  112. Low-dose Radiation Combined With Neoadjuvant Immunochemotherapy for Esophageal Squamous Cell Carcinoma
  113. Cadonilimab Combined With Liposomal Irinotecan Plus Leucovorin and Fluorouracil for Advanced Cholangiocarcinoma
  114. Nanoliposomal Irinotecan, Oxaliplatin Plus Capecitabine as Conversion Therapy of Locally Advanced Colorectal Cancer
  115. Cadonilimab in Combination With Lenvatinib and Hepatic Arterial Infusion Chemotherapy (HAIC) for the Treatment of Unresectable Hepatocellular Carcinoma
  116. A Study Comparing Neoadjuvant Chemoimmunotherapy and Immuno-consolidationafter Compared With Immunoconsolidation After Radical Chemoradiotherapy for Stage III Potentially Resectable NSCLC
  117. A Single-arm Phase II Clinical Study of the Efficacy and Safety of Camrelizumab Combined With GEMOX for Unresectable GBCs
  118. Outpatient and Intermittent Dosing of Elranatamab in Relapsed/Refractory Multiple Myeloma
  119. Efficacy of Dihydroartemisinin for Treating PCOS
  120. A Study of BL-M07D1, BL-M07D1+Pertuzumab and BL-M07D1+Pertuzumab+Docetaxel in Patients With Unresectable Locally Advanced or Metastatic HER2-positive Breast Cancer
  121. Combination Therapy for BRAF-V600E Metastatic CRCm
  122. PRONTO Trial (PRophylactic Versus ON-demand Use of TOcilizumab)
  123. This is a Phase II, Open-label, Multicentre Study of Zanubrutinib-containing Regimens in Patients With Newly Diagnosed Mantle Cell Lymphoma
  124. Clinical Trial to Evaluate BO-112 in Patients With Basal Cell Carcinoma (BCC)
  125. QL1706 Plus Chemotherapy as Neoadjuvant Therapy in Early High-Risk TNBC Breast Cancer
  126. Study of QLS31905 and/or QL1706 Combination With Chemotherapy in the Advanced Malignant Solid Tumors
  127. Safety and Efficacy of Neoadjuvant Immunochemotherapy in Elderly Patients With Resectable Esophageal Cancer
  128. The Efficacy and Safety of HIPEC Combined With PD-1 and SOX Chemotherapy for the Translational Treatment of GC or EGJC With PM
  129. ctDNA-MRD Guided Consolidation Toripalimab in Stage IB-IIIA NSCLC
  130. Durvalumab + Intraductal Radiofrequency Ablation (ID-RFA) in Extrahepatic Cholangiocarcinoma
  131. Nimotuzumab Concurrent With Chemoradiotherapy for Patients With Unresectable Esophageal Squamous Cell Carcinoma
  132. Chemotherapy Plus Bevacizumab and Anti-PD-1 Followed by Induction Therapy of Chemotherapy Plus Bevacizumab
  133. Volrustomig Priming Regimens Exploratory Phase II Platform Study
  134. Safety and Efficacy of 3 Dose Levels of NMD670 in Adult Patients With Myasthenia Gravis
  135. Study of VA Combined With HAAG Regimen in Newly Diagnosed Intermediate and High-risk AML Patients
  136. FMT+Immunotherapy+Chemotherapy as First-line Treatment for Driver-gene Negative Advanced NSCLC
  137. Cangpo Liujun Prescription on Cancer-related Fatigue in Advanced Colorectal Cancer With Spleen Deficiency and Dampness Excess
  138. Chidamide+Decitabine Plus Anti-PD-1 Antibody in PD-1 Inhibitor Failed Patients With Classical Hodgkin Lymphoma.
  139. Low Dose Mosunetuzumab for the Treatment of Patients With Indolent B-Cell Lymphoma
  140. Fruquintinib Plus Camrelizumab and HAIC in the Treatment of Non-MSI-H Advanced Colorectal Cancer
  141. A Phase II Study of Neoadjuvant Immunotherapy in Combination With Chemotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma
  142. A Study of BL-M07D1+PD-1 Monoclonal Antibody and BL-M07D1+PD-1 Monoclonal Antibody+Capecitabine in Patients With Locally Advanced or Metastatic HER2-positive Gastric or Gastroesophageal Junction Adenocarcinoma
  143. Psilocybin-assisted Existential, Attachment and RelationaL (PEARL) Therapy for Patients With Advanced Cancer
  144. Phase II Trial of Pemigatinib in Combination With Atezolizumab and Bevacizumab for Treatment of Advanced Cholangiocarcinoma With FGFR2 Fusion
  145. Decitabine, Venetoclax and Blinatumomab for Maintenance Following HSCT in Patients With Ph-Negative B-ALL
  146. Nab-Paclitaxel Plus Cisplatin With Concurrent Radiotherapy for Patients With Locally Advanced Cervical Cancer: A Multicentre, Single-arm, Phase II Trial.
  147. Surufatinib Combined With Tislelizumab in Advanced Lung Cancer With Neuroendocrine Differentiation
  148. Safety & Efficacy of Peg-ASP-based CCRT in Early Stage ENKTL
  149. The Efficacy and Safety of Tislelizumab Combined With Anlotinib and S1 Plus Oxaliplatin as Neoadjuvant Therapy for the Locally Advanced Adenocarcinoma of Esophagogastric Junction
  150. Nimotuzumab Plus AG in Pancreatic Cancer With Liver Metastasis
  151. Irinotecan, TAS-102 Plus Bevacizumab as a Third-Line or Beyond Therapy in mCRC Patients
  152. SBRT Combined With Nimotuzumab and Mono-chemotherapy in Locally Advanced Pancreatic Cancer
  153. Phase II Study of Liposomal Irinotecan for Advanced Refractory Gastric Cancer
  154. A Phase II Study of SSGJ-707 Combination Therapy in Advanced NSCLC Patients
  155. A Phase 2 Study to Evaluate the Efficacy, Safety and Pharmacokinetics of YL202 in Patients With BC
  156. A Study of BL-B01D1+PD-1 Monoclonal Antibody in Patients With Extensive-stage Small Cell Lung Cancer
  157. A Clinical Study of MK-2870 Alone or With Chemotherapy to Treat Gastrointestinal Cancers (MK-9999-02A)
  158. Safety, Preliminary Effectiveness of BNT327, an Investigational Therapy for Patients With Small-cell Lung Cancer in Combination With Chemotherapy
  159. Hematoporphyrin Photodynamic Therapy for Esophageal Cancer
  160. Effect of Vitamin C on Postoperative Pulmonary Complications After Intracranial Tumor Surgery
  161. A Study of Emapalumab for Pediatric Aplastic Anemia
  162. Lattice Radiotherapy for Dose-Escalated Palliation of Bulky Tumors
  163. Perioperative Surufatinib Plus Sintilimab Combined With Chemotherapy in Gastric/Gastroesophageal Junction Adenocarcinoma
  164. A Study Comparing Abemaciclib Plus Temozolomide to Temozolomide Monotherapy in Children and Young Adults With High-grade Glioma Following Radiotherapy
  165. Sintilimab After Concurrent Chemoradiotherapy in Elderly Patients With Esophageal Squamous Cell Carcinoma
  166. FMT+SOX+Sintilimab as First-line Treatment for Advanced Gastric Cancer
  167. PEARL Study: PotEntial of Asciminib in the eaRly Treatment of CML
  168. Adebrelimab Plus Chemotherapy, Bevacizumab and Fluzoparib in Platinum-Sensitive Relapsed Ovarian Cancer
  169. Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas
  170. TIP Regimen Combined With Triplizumab Neoadjuvant Therapy for Locally Advanced Penile Cancer
  171. A Study of FDA022-BB05 in Advanced/Metastatic Solid Tumors
  172. PD-1 Antibody and Sapropterin Dihydrochloride in Patients With PDAC
  173. A Phase II Clinical Study of Epigallocatechin-3-gallate in Patients With Esophageal Squamous Cancer
  174. Neoadjuvant Cadonilimab Combined With Anlotinib in Locally Advanced Resectable Esophageal Squamous Cell Carcinoma
  175. A Prospective, Single-arm, Multicenter Phase II Clinical Study of HAIC in Combination With Adebrelimab and Bevacizumab for Potentially Resectable Hepatocellular Carcinoma
  176. Boost Irradiation to the Supraclavicular Area Among High Risk cN3c Breast Cancer Patients
  177. Study of ADCs Combined With Adebrelimab in HER2-negative Advanced Breast Cancer
  178. Efficacy of Pola-RCHP-X vs Pola-RCHP in Untreated DLBCL
  179. First-line Anlotinib Combined With Penpulimab for Advanced Pheochromocytoma: A Single-arm, Multicenter, Prospective Phase II Study
  180. Deep-sea Fish Oil for Prevention of Acute Radiation-induced Esophagitis
  181. The SAPPHO Study: A Single-Arm, Phase II Study of Sequential Therapy With Curative Intent in de Novo HER2+ Metastatic Breast Cancer
  182. A Prospective, Single-arm, Phase II Clinical Trial to Evaluate the Efficacy and Safety of Tafolecimab and Sintilimab Combined With Chemotherapy in Patients With Advanced or Metastatic Driver Gene-negative Non-small Cell Lung Cancer After Failure of First-line Immunotherapy.
  183. Phase II Clinical Study of SHR-A1811 in Patients With HER2 Expression / Amplification of Locally Advanced Unresectable or Recurrent Metastatic Biliary Tract Cancer
  184. Fruquintinib Plus S-1 and Raltitrexed (RSF) for mCRC
  185. SBRT, Chemotherapy, and AK112 Neoadjuvant Therapy for Triple-negative Breast Cancer (TNBC)
  186. Efficacy and Resistance Mechanisms of IP in NSCLC With Leptomeningeal Metastases
  187. A Dose Finding Study of Debio 4228 in Participants With Locally Advanced/Metastatic Prostate Cancer
  188. Surufatinib Combined With Carboplatin/Paclitaxel and Surufatinib Combined With Olaparib as First-line and Maintenance Therapy for Newly Diagnosed High-risk Ovarian Cancer
  189. Testing Ipatasertib as Potentially Targeted Treatment in Cancers With AKT Genetic Changes (MATCH - Subprotocol Z1K)
  190. Phase II Study of the Combination of Durvalumab (MEDI4736) (PDL1 Inhibitor) and Olaparib (PARP Inhibitor) in Advanced Cholangiocarcinoma After Initial Chemotherapy and Durvalumab (BIL-PPP)
  191. Irinotecan Liposomes in Combination With Nituzumab for the Treatment of Recurrent/Metastatic Nasopharyngeal Carcinoma After Failure of First-Line or Higher Immunotherapy
  192. Double Dose of Third-generation EGFR-TKI Plus Intrathecal Pemetrexed Versus Double Dose of Third-generation EGFR-TKI in Patients With LM Progression Following the Treatment of Routine Dose of Third-generation EGFR-TKI
  193. A Clinical Study of SPH5030 Tablets in the Treatment of Her2-positive/Mutated Biliary Tract OR Colorectal Cancer Patients.
  194. Study of A Venetoclax-based, Anthracycline-free Regimen in Newly Diagnosed CBFΞ²::MYH11(+) AML
  195. Daratumumab, Bortezomib, Cyclophosphamide, and Dexamethasone Therapy for Patients With MIDD
  196. Serplulimab Plus Chemotherapy for Early-stage ER+/HER2- Breast Cancer

Phase 1-2:

  1. Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors
  2. A First-In Human (FIH) Trial to Find Out if REGN10597 is Safe and How Well it Works for Adult Participants With Advanced Solid Organ Malignancies
  3. MB-dNPM1-TCR.1 in Relapsed/Refractory AML
  4. Safety and Efficacy of Intraperitoneal Injection of METR-NK Cells as Neoadjuvant Therapy for Advanced Epithelial Ovarian Cancer
  5. Prehabilitation for EOC, Fallopian Tube, Primary Peritoneal Carcinoma and Pancreatic Cancer w/ NACT
  6. A Clinical Study of Puesta Mesylate for Injection in Patients With Solid Tumors
  7. Enfortumab Vedotin With Radiation for Locally Advanced Bladder Cancer (CONSOLIDATE)
  8. Substudy 06D: Combination Therapies in Second Line (2L) Gastroesophageal Adenocarcinoma (MK-3475-06D/Keymaker-U06)
  9. Clinical Trial of TB511 in Advanced Solid Tumors
  10. Phase Ib/II Study of HRS2398 in Combination With Adebrelimab in Patients With Advanced Solid Tumors
  11. Evaluation of The Efficacy And Safety of PD-1 + IL-2 Combined With Capox Treatment After Loop Colostomy Surgery in Left-sided Colorectal Cancer Patients Complicating Acute Obstruction
  12. Linperlisib Combined With Chidamide in Patients With PTCL
  13. Evaluation of Programmed Death Ligand 1 (PDL1) Response to Treatment in Patient-derived Organoids and Immune-marker Positron Emission Tomography (PET) Scanning in Non-small Cell Lung Cancer (NSCLC)
  14. Dose Escalation Study of ZG006 in Participants With Advanced Small Cell Lung Cancer or Neuroendocrine Carcinoma, Followed by Dose Expansion Study in Participants With Neuroendocrine Carcinoma.
  15. Sequential CAR-T Cells Therapy for CD5/CD7 Positive T-cell Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma Using CD5/CD7-Specific CAR-T Cells
  16. Safety and Tolerability Study of GIM-531 in Advanced Solid Tumors
  17. Liposomal Irinotecan Plus Bevacizumab in Irinotecan-refractory Metastatic Colorectal Cancer
  18. A Study of Pembrolizumab in Combination With Investigational Agents in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01B/LIGHTBEAM-U01)
  19. EXL01 in Combination With Nivolumab for Advanced NSCLC Refractory to Immunotherapy.
  20. A Study of TQB2102 for Injection in the Treatment of HER2-positive Biliary Tract Cancer
  21. Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)
  22. GH21 Combined With D-1553 With Advanced Solid Tumors
  23. Frontline Combination CAR-T Cell Therapy for Multiple Myeloma or Plasmacytoma
  24. Clinical Study of SHR-A1921 Combined With Adebrelimab and SHR-8068 With or Without Carboplatin in the Treatment of Advanced NSCLC
  25. CAN1012 Combined With PD-1 in Patients With Solid Tumors
  26. Sequential CAR-T Cells Targeting CD33/CD123 in Patients With Acute Myelocytic Leukemia AML
  27. A Study to Investigate APL-5125 in Adults With Advanced Solid Tumors
  28. Exploratory Clinical Study of HRS-4642 Combined With Adebelimab in the Treatment of Advanced Pancreatic Cancer
  29. Enfortumab Vedotin and Stereotactic Radiation for Localized, Cisplatin Ineligible Muscle Invasive Bladder Cancer
  30. Study to Evaluate a New Method to Detect Residual Tumours During Surgery for Prostate Cancer Using Confocal Microscopy
  31. A Study to Evaluate the Efficacy and Safety of QLF31907 Combination Therapy in Patients With Advanced Malignant Tumors
  32. Lymphocyte Support to SBRT in Patients With Oligo-metastatic Solid Cancer
  33. A Trial of SHR-A2102 With or Without Antitumor Therapy in Advanced Solid Tumors
  34. Yttrium-90 (Y90) Radioembolization for the Treatment of Early Stage Renal Cell Carcinoma, The RENEGADE Trial
  35. FOLFOX Plus Lenvatinib Adjuvant Therapy for Hepatocellular Carcinoma Post-Liver Transplantation
  36. Multimodal Imaging in Rectal Cancer & Pancreatic Cancer
  37. Somatostatin-Receptors (SSTR)-Agonist [212Pb]VMT-alpha-NET in Metastatic or Inoperable SSTR+ Gastrointestinal Neuroendocrine Tumor and Pheochromocytoma/Paraganglioma Previously Treated With Systemic Targeted Radioligand Therapy
  38. A Multicenter Phase 1b/2 Study of Adagrasib, Cetuximab, and Cemiplimab for Metastatic Colorectal Cancer Harboring KRAS G12C Mutations
  39. Sintilimab Combined With LDRT for Neoadjuvant Treatment of Locally Advanced dMMR/MSI-H Gastric Cancer
  40. Testing the Addition of ASTX660 (Tolinapant) to the Usual Chemotherapy Treatment (Paclitaxel With or Without Bevacizumab) in Patients With Recurrent Ovarian Cancer

Phase 1:

  1. A Trial of SHR-4849 in Advanced Solid Tumors
  2. First in Human Study of CDR404 in HLA-A*02:01 Participants With MAGE-A4 Expressing Solid Tumors
  3. A Phase I Study to Assess the Tolerability of 225Ac-DOTATATE in Patients With Refractory and Relapsing Multiple Myeloma Expressing Somatostatin Receptors
  4. A Study to Learn About the Study Medicine PF-07934040 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Genetic Mutation.
  5. Study in Patients With Advanced Solid Malignancies to Evaluate the Safety of FTL001
  6. A Study of the ILB-3101 in Patients With Advanced Solid Tumors
  7. Eltanexor and Venetoclax in Relapsed or Refractory Myelodysplastic Syndrome and Acute Myeloid Leukemia
  8. First-in-human Study of Interferon-y PET Imaging to Assess Response to Immunotherapy
  9. A Phase 1 Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of YL201 in Advanced Solid Tumors
  10. Engineered Dendritic Cell Vaccines for Multiple Myeloma
  11. Study of ISM3412 in Participants With Locally Advanced/Metastatic Solid Tumors
  12. Triapine in Combination With Temozolomide for the Treatment of Patients With Recurrent Glioblastoma
  13. A Phase l Study of By101921, an Oral PARP7 Inhibitor, in Patients With Advanced Solid Tumors
  14. A Study of FZ-AD005 in Patients With Advanced Solid Tumors
  15. A Clinical Research About CD70-targeted CAR-NKT Cells Therapy Advanced Malignant Solid Tumors
  16. A Study of APL-1501 Extended Release Capsules Compared to APL-1202 Immediate Release Tablets in Healthy Volunteers
  17. A Trial of AK104 or AK112 in Combination With Axitinib in Patients With Metastatic Mucosal Melanoma
  18. CD5-deleted Chimeric Antigen Receptor Cells (Senza5 CART5) for T Cell Non-Hodgkin Lymphoma (NHL)
  19. A Phase I Study Investigating the Combination of the Ziftomenib, Venetoclax and Azacitidine in Pediatric Relapsed and Refractory Acute Leukemias
  20. Phase I Trial to Determine the Dose and Evaluate the PK of Lutetium Lu 177 Edotreotide Therapy in Pediatric Participants With SSTR-positive Tumors
  21. Study in Patients With Advanced Solid Tumors to Evaluate the Safety of FTL008.16
  22. A Study of Zolbetuximab With Chemotherapy in Adults With Pancreatic Cancer
  23. Clinical Study of T3011 Intravesical Instillation for Treatment of NMIBC Patients
  24. A Study of SKB518 in Patients With Advanced Solid Tumors
  25. Autologous CD22 CAR T Cells Following Commercial CD19 CAR T Cells in B Cell Malignancies
  26. A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Clinical Activity of GSK5733584 for Injection in Participants With Advanced Solid Tumors
  27. Clinical Trial of Targeted Alpha Therapy for Prostate Cancer
  28. A Study Comparing Pre- and Post-Change Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma
  29. Phase 1 First-in-Human Study of BGB-C354 Alone and in Combination With Tislelizumab in Participants With Advanced Solid Tumors
  30. A Phase I Clinical Study of QLC1101 in Patients With Advanced Solid Tumors
  31. Ziftomenib Maintenance Post Allo-HCT
  32. A Phase 1b Study of Psilocybin Assisted Psychotherapy to Address Fear of Recurrence
  33. A Phase 1 Study of BGB-B2033, Alone or in Combination With Tislelizumab, in Participants With Advanced or Metastatic Solid Tumors
  34. Study of BMS-986497 (ORM-6151) in Participants With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome
  35. CBM588 Capsules in Combination With Nivolumab and Ipilimumab for the Treatment of Advanced Stage Kidney Cancer
  36. A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies
  37. Study Evaluating ISM8207 in Participants With Advanced Solid Tumors and Relapsed/Refractory B-Cell Lymphoma
  38. Neoadjuvant Radio-chemotherapy Safety Pilot Study in Patients With Glioblastoma
  39. A Study in Advanced/Metastatic Solid Tumors With the Study Medicine (PF-07329640) When Given Alone or In Combination
  40. A Phase I Study of Decitabine, Lisaftoclax, and Olverembatinib in Patients With Advanced Chronic Myeloid Leukemia and Philadelphia Chromosome-Positive Acute Myeloid Leukemia
  41. A Clinical Trial of TQB3117 Tablets in Patients With Advanced Malignant Cancer
  42. CD19/CD22 CAR-T Cells in Adults With R/R ALL or NHL
  43. A Trial to Evaluate the Safety and Efficacy of NCR300 in Preventing Recurrence of Acute Myeloid Leukemia(AML) After Transplantation
  44. A Study of LY4170156 in Participants With Selected Advanced Solid Tumors
  45. TGRX-326 Pharmacokinetic Mass Balance
  46. A Study of ARV-393 in Relapsed/Refractory Non-Hodgkin Lymphoma.
  47. Ξ³Ξ΄ T-PD-1 Ab Cells in the Treatment of Advanced Solid Tumors
  48. OPC5: Pressurized IntraThoracic Aerosol Chemotherapy (PITAC) in Patients With Malignant Pleural Effusion.
  49. Technetium [99mTc]-H7ND in Patients With Gastrointestinal Malignancies and Healthy Volunteers
  50. An Investigational Scan (124I-hJAA-F11 PET/CT) for Diagnosing Lung Cancer
  51. Humanized CD19-Specific CAR T Cells for the Treatment of Patients With Positive Relapsed or Refractory CD19 Positive B-Cell Acute Lymphoblastic Leukemia
  52. Vaccine Therapy in Treating Patients With Metastatic Solid Tumors
  53. ACE2016 in Adult Subjects With Locally Advanced or Metastatic Solid Tumors Expressing Epidermal Growth Factor Receptor (EGFR)
  54. BTX-A51 in Patients With Liposarcoma
  55. M9466 as Single Agent or in Combination With Tuvusertib in Advanced Solid Tumors (DDRiver 501)
  56. IM83 Clinical Study of CAR-T Cell Therapy in Patients With Relapsed or Refractory Osteosarcoma
  57. Exercise-based Rehabilitation to Treat Persistent Chemotherapy Induced Peripheral Neuropathy (CIPN)
  58. A Phase 1b Study to Investigate Safety and Tolerability of ARGX-119 in Adult Participants With DOK7-Congenital Myasthenic Syndromes (CMS)
  59. Targeting CD19/CD20 Dual-targeted Cell in Patients With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma
  60. QTX3046 in Patients With KRAS G12D Mutations
  61. PIRATES Phase I Trial
  62. Dose-escalation Study of Ultra-high Dose Ablative Radiosurgery With Immunotherapy for Bulky Metastatic Cancer Patients
  63. TQB2928 Injection Combined Anlotinib Hydrochloride Capsule in Recurrent/Metastatic Osteosarcoma and Other Solid Tumors
  64. Study of IBI3005 in Subjects With Unresectable, Locally Advanced or Metastatic Solid Tumors
  65. A Study on the Safety and Preliminary Efficacy of NK042 in the Treatment of Malignant Ascites
  66. Safety and Efficacy of Whole Brain LDRT+ICI+Intrathecal Chemotherapy in Refractory Meningeal Metastasis of Lung Cancer
  67. A Study of VET3-TGI in Patients With Solid Tumors
  68. Phase I Study of Q702 With Azacitidine and Venetoclax for Relapsed or Refractory Acute Myeloid Leukemia
  69. A Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of TT125-802 in Subjects With Advanced Solid Tumors
  70. R-5780-01 In Combination With PD-1 Checkpoint Inhibitors (Checkpoint Protein on Immune Cells Called T Cells) in Patients With Solid Tumors
  71. CHemotherapy And Stool Transplant in PDAC (CHASe-PDAC)
  72. Pembrolizumab Plus CA-4948 for the Treatment of Patients With Progressive Metastatic Urothelial Cancer Despite Prior Immunotherapy
  73. NXP800 for the Treatment of Patients With Advanced or Metastatic Cholangiocarcinoma
  74. Mitoxantrone for Venetoclax Resistant Acute Myeloid Leukemia
  75. A Phase I Study Investigating the Combination of the Menin Inhibitor Ziftomenib With Venetoclax and Gemtuzumab in Pediatric Patients With Acute Myeloid Leukemia
  76. A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors
  77. A Clinical Study of TQB3107 Tablets in Patients With Malignant Tumors
  78. Study to Assess Safety and Tolerability of OPN-6602 in Subjects With Relapsed and/or Refractory Multiple Myeloma
  79. Clinical Trial of BT02 in Patients With Advanced Solid Tumors
  80. STARLITE for Unresectable High-Grade Gliomas
  81. Preoperative Adjuvant SOX Plus PL-1 Antibody and FLOT Plus PD-1 Antibody for Locally Advanced dMMR Gastric Cancer

Early Phase 1:

  1. Targeting NUDT21 siRNA Drugs for Patients With Refractory Retinoblastoma
  2. A Study of Tumor Neoantigen-specific T Cells in the Treatment of Advanced Solid Tumors
  3. First Human Trial of Targeting MDM2/MDMX PET Imaging
  4. Clinical Study of Allogeneic VΞ³9VΞ΄2 T Cells in the Treatment of Brain Malignant Glioma
  5. 68Ga-FAPI-JH04 PET/CT: Dosimetry and Biodistribution Studies
  6. Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Peripheral Blood Stem Cell Transplantation in Adult Patients at High-risk for Primary Graft Failure Secondary to Donor Specific Antibodies
  7. A Bowel Management Program (Retrograde Rectal Enema) for the Treatment of Low Anterior Resection Syndrome in Rectal Cancer Patients
  8. An Exploratory Clinical Study of GC012F Injection for the Treatment of Refractory Generalized Myasthenia Gravis
  9. Relationship bw Image-deriv Features of Intraoperative ICG Visualiz of NVBs During RARP & Functional Outcome
  10. MRD-positive Colorectal Cancer Patients Combined With Personalized Immune Regulation Diagnosis
  11. Safety and Efficacy of Metabolically Armed CD19 CAR-T Cells (Meta10-19) in the Treatment of Relapsed and/or Refractory CD19-positive B Cell Hematological Malignancies Clinical Research
  12. 18F-AraG PET/CT as a Non-Invasive Imaging Biomarker for Chemoradiation Treatment Response in Esophageal Cancer
  13. Sequential Therapies Modeled on Evolutionary Dynamics for Breast Cancer
  14. [18F] PSMA-1007 PET/CT in Metastatic Clear Cell Renal Cell Carcinoma
  15. Chemokine and Co-stimulatory Molecule-modified Mesenchymal Stem Cells for the Treatment of Advanced Colorectal Cancer
  16. 99mTc-QULIC-5-P1 SPECT Imaging in Patients With Prostate Cancer
  17. Neoantigen Vaccine Plus Capecitabine as Adjuvant Therapy for Intrahepatic Cholangiocarcinoma After Radical Resection
  18. 68Ga-AAZTA-093 PET/CT: First-in-human Study
  19. Neoantigen Reactive T Cells c for Chinese Patients With Advanced Gastric Cancer
  20. 68Ga-NOTA-RM26 PET/CT in Glioma Patients
  21. A Clinical Trial Evaluating the Safety and Efficacy of Intravenous CD-801 in Treating Advanced HCC Patients
  22. Application of 68GA-labeled CD73 Targeting Probe PET/CT Imaging in the Diagnosis of Breast Cancer
  23. Personalized Dendritic Cell Vaccine Pilot for High Risk TNBC After Neoadjuvant Therapy
  24. A Dose Escalating Study of CD19/CD22/BCMA CAR-T Therapy in Relapsed or Refractory B Cell Non-Hodgkin Lymphoma(NHL)
  25. [68Ga]Ga-Sa-DABI-4 PET Imaging of Stimulator of Interferon Gene Expression in Cancer Patients
  26. An Exploratory Study of Efficacy and Safety of Iruplinalkib Tablets in Patients With ROS1 Positive Non-small Cell Lung Cancer
  27. CYTALUXβ„Άfor the Intraoperative Imaging of Prostate Cancer
  28. AMT-676 in Patients With Advanced Solid Tumors
  29. HCQ in Resectable Localized Prostate Cancer
  30. Study of CT071 Injection in High Risk Newly Diagnosed Multiple Myeloma

Phase Not Applicable:

  1. Adherence to Oral Therapies in Advanced Breast and Prostate Cancers
  2. Prehabilitation in Oncological Patients Undergoing Major Gastrointestinal Surgery (PROGRESS)
  3. Multi-Modal Image Fusion for Precision Prostate Biopsy Navigation
  4. Evaluating the Impact of a Virtually Supervised Exercise Intervention and Group Counseling on Inflammation and the Microbiome of Smokers at High Risk for Lung Cancer, BE FIT Trial
  5. Evaluation of the Effects of Using Cooling Pillowcases, on the Symptoms of Hot Flushes, Sleep and Life Quality
  6. Oncological and Perioperative Outcomes of Laparoscopic Versus Robotic Partial Nephrectomy for Treatment of Renal Tumors.
  7. Study to Assess the Impact of the Urine Test Cxbladder Detect+ on the Number of Cystoscopies Performed on Patients With Invisible Blood in Their Urine.
  8. Home-Combo: an Online Home-based Combined Exercise Intervention for Women With Breast Cancer
  9. Addressing Financial and Social Needs Among Patients With Cancer
  10. Preparation for Medical and Surgical Procedures in Oncogeriatry.
  11. The Efficacy of Hibiscus Sabdariffa in Xerostomia
  12. Clinical Treatment of Refractory Breast Cancer Based on Organoid Drug Sensitivity Results
  13. Electrosurgical Bipolar Systems Versus Conventional Electrocautery After SLNBx
  14. Polycystic Ovary Syndrome and Education
  15. Evaluation of a Range of Dermo-cosmetic Products to Treat Skin and Nail Toxicity Linked to Bispecific Anti-GPRC5D Bispecific Antibodies in Multiple Myeloma Patients". Myeloma". Descriptive Pilot Study
  16. Ablative Stereotactic MR-Guided Adaptive Reirradiation
  17. Dynamics of Motivational Factors for Physical Activity and Nutrition in Oncogeriatrics
  18. Perioperative Multimodal Analgesia Protocol for Supratentorial Craniotomy
  19. 4:3 Intermittent Fasting Intervention in Adults With Breast Cancer and Overweight or Obesity
  20. PeLear CCC: Proyecto Latino Contra Cancer Colorectal
  21. Effect of Lidocaine on Postoperative Pain and Long-term Survival in Elderly Patients Undergoing Colorectal Surgery
  22. Efficacy of TEAS on Chronic Pain and Survival in Patients Undergoing Hepatectomy
  23. Clinical Effectiveness of Microwave Ablation Using Starwave Microwave Generator for Hepatic Malignancies
  24. The Use of Remote Monitoring to Improve Patient-Reported Outcomes and Readmission Rates Following Radical Cystectomy
  25. Myosteatosis in Oeso-gastric Cancer: Clinical Impacts
  26. Effect of Bupivacaine Liposome Anterior Serratus Deep Block on Chronic Pain After Breast Cancer Surgery: a Randomized Controlled Study
  27. Effectiveness of Robotic Surgery for Right Colon Cancer
  28. Cytosponge in Surveillance After Endoscopic Submucosal Dissection for Esophageal Squamous Cell Carcinoma
  29. Topical Application of PRF Before Radiation Therapy
  30. Effects of Lymph Drainage on Patients With Axillary Web Syndrome
  31. A Pilot Study of Genetic Testing Uptake Through Enhanced Oncology Nurse-Led Intervention
  32. Effectiveness of a Combined Diet and Mindfulness Program on Weight Loss in Breast Cancer Survivors
  33. Lifei Xiaoji Wan in Treatment of Advanced NSCLC
  34. Psycho-Spiritual Management for Patients With Advanced Cancer and Their Family Caregivers
  35. Assessment the sExual Quality of Life in Breast Cancer Patients Receiving oncoSexology Supportive Care on Proactive Versus On-request
  36. The Impact of Probiotic on Survival and Treatment Response in Metastatic Non-small Cell Lung Cancer Patients
  37. Evaluation of Response by FLT PET in Mesothelioma
  38. A Clinical Study Evaluating the Safety and Efficacy of ZRMT Regimen in the Treatment of PCNSL
  39. Resistance Exercise and Creatine in Colorectal Cancer
  40. Dynamic Whole-body PET/CT Imaging in Clinical Oncology
  41. Evaluation of the Efficacy and Safety of Indocyanine Green Tracing in 3D Fluorescent Laparoscopic Lymph Node Dissection for Gastric Cancer
  42. Diagnostic HER2DX-guided Treatment for patIents wIth Early-stage HER2-positive Breast Cancer
  43. Research on Early Diagnosis and Clinical Transformation of Nuclide Probe Based on Bioorthogonal-gastric Cancer Mucin Target Visualization
  44. Patient-derived Organoid Drug Sensitivity Guided Treatment for Recurrent Small Cell Lung Cancer
  45. PrOton Pulsed reduCed dOse Rate Radiotherapy for Recurrent CNS maligNancies Trial
  46. Self-Administered Relaxing Acupressure to Reduce Fatigue in Adolescent and Young Adult Cancer Survivors
  47. Effects of a 3D-Printed Port-A Catheter Model Training Course
  48. Impact of Respiratory Rehabilitation on Quality of Life in Patients With Metastatic Non-small Cell Lung Cancer Treated With Immunotherapy and Chemotherapy in the Maintenance Phase
  49. Safety and Efficacy of Recombinant Human Thyroid Stimulating Hormone for Adjuvant Diagnosis in Patients With Locally Advanced/Metastatic Differentiated Thyroid Cancer
  50. Risk Assessment Evaluation for Identifying Participants at High Risk for Stomach Cancer
  51. Feasibility Study of ABC for Women Treated for Breast Cancer
  52. An Education and Navigation Support Tool to Improve Participation in Care Coordination Among Patients With Locally Advanced, Metastatic and Unresectable Bladder Cancer and Their Caregivers
  53. Effects of a Combined Program of Pelvic Floor Muscle Training and Yoga
  54. Cancer Prevention Among Individuals With Mental Ill-health: Patient Navigation for Primary Cancer Prevention
  55. Molecular Imaging of Gastric Cancer Metastatic Lymph Nodes with 99mTc-3PRGD2 Probe.
  56. Parkinsonism-Related Oscillations in the Cortico-Basal Ganglia-Thalamic Network During Movement: Beyond the Frequency Range
  57. Comparing Valve-regulated Pleural Drainage to Traditional Closed Chest Tube Drainage
  58. Preoperative Physical Activity Improvement With the Use of Activity Trackers Before Radical Cystectomy (PreAct)
  59. Quilting Sutures After Mastectomy
  60. Contribution of the VERITON-CT Camera in Prostate Bone Radiostereotaxy
  61. The Effect of a Psychosomatic Symptom Intervention Program on the Primary Treatment of Differentiated Thyroid Cancer
  62. A Virtual, Group-Based, Expressive Writing Intervention for Survivors of Adolescent and Young Adult Cancer
  63. The Effect of Dimenhydrinate on Postoperative Nausea and Vomiting After Abdominal Hysterectomy: Randomized-controlled Trial
  64. Pilot RCT Laser Hair Depilation Darker Skin Pilonidal Disease
  65. The Preventive Role of Fractionated Laser Resurfacing Against Actinic Neoplasia in an At-Risk Geriatric Population
  66. Multimodal Prehabilitation in Colorectal Cancer Patients
  67. First in Human Study for the Assessment of Safety and Initial Performance of the EAS1 System
  68. The Impact of Physical Activity Versus Dietary Energy Restriction on Tumour and Muscle Protein Synthesis in Prostate Cancer Patients
  69. Prophylactic Antibiotics in Endoscopic Secondary Prevention of Gastroesophageal Variceal Bleeding
  70. Rural Adult and Youth Sun Protection Study
  71. Physical Activity for Adults in the Ontario Breast Screening Program
  72. Tobacco, Alcohol and Cancerization of the Oral Mucosa (TACO)
  73. Patient-derived Organoid Drug Sensitivity Guided Treatment for Drug-resistant Recurrent Non-Small Cell Lung Cancer
  74. Postoperative Analgesia in Major Gynecological Cancer Surgeries
  75. Peginterferon Ξ±-2b Combined CO2 Laser in Condylomata Acuminata
  76. Palliative Radiotherapy in Symptomatic Pelvic Soft Tissue Tumors
  77. Dual-port Trans-subclavian Thyroid Endoscopic Surgery
  78. Stress Management Intervention Among Breast and Gynecologic Cancer Patients in Viet Nam
  79. Optimizing Bronchopulmonary Cancer Screening
  80. Impact of an Early Warning System on the Prognosis of Patients With Hematological Malignancies Receiving Intensive Chemotherapy With or Without Hematopoietic Cell Transplantation.
  81. Accelerated Pulmonary Rehabilitation in the Preoperative Period
  82. Ready to Sail: Evaluating Sailing's Feasibility as Ergotherapy
  83. Study on Effect of Robotic Versus Laparoscopic Surgical Technology on Genitourinary Function After Total Mesorectal Excision for Rectal Cancer
  84. A Cervical Cancer Prevention Program Kenya: Overcoming Obstacles to Care, Promoting Understanding of HPV Natural History
  85. Are CK+/CD45+ Double-Positive Circulating Cells of Tumor-origin? Characterization in METAstatic Breast Cancer
  86. Adebrelimab Combined With Chemoradiotherapy for Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma (ESCC)
  87. 3D Port-A Catheter Model for New Staff
  88. Reducing Urban Cervical Cancer Disparities
  89. Brain MRF in Children, Adolescents and Young Adults With Acute Leukemia
  90. Access to Genetic Testing in Underserved Patients With Cancer
  91. Clinical Efficacy of Tumour Treatment Vaccine (TTV) Combined With PD-1 in the Treatment of Relapsed Refractory Advanced Solid Tumours
  92. Post-operative Radiotherapy Omission in Selected Patients With Early Breast Cancer Trial International Validation Experience
  93. A Study Comparing a Disposable Flexible Cystoscope With Reusable Scopes in Adult Patients.
  94. Outpatient Versus Tele Rehabilitation Among Post-surgical Breast Cancer Survivors
  95. Exercise Prehabilitation for Locoregional Esophageal Cancer
  96. Efficacy and Safety of Sugammadex in Thoracoscopy Thymectomy for Chinese Adults With Myasthenia Gravis
  97. Study of Cellular Heterogeneity in Patients With Mastocytosis
  98. Efficacy of a Proactive Approach to Death Thoughts in People With Advanced Cancer
  99. Ceftolozane/Tazobactam vs. Piperacillin/Tazobactam for the Treatment of Bacteremia in Hemato-oncological Patients
  100. mPATH-Cloud for Colorectal Cancer Screening
  101. Conversations in Light and Shadow: Assessing Phototherapy's Impact on Breast Cancer Patients
  102. Cold Atmospheric Plasma for the Endoscopic Treatment of Duodenal Polyps in Patients With Familial Adenomatous Polyposis
  103. Effect of Hypoxia on FMISO PET to Response to Lu-177 PSMA Treatment
  104. The Clinical Application of Ultramicro-flow Technique in the Treatment of Benign Uterine Tumors With High-intensity Focused Ultrasound
  105. Polygenic Risk Stratification Combined With mpMRI to Identify Clinically Relevant Prostate Cancer
  106. MRg-NIRS Imaging System Breast Cancer Trial
  107. Minimally Invasive Simple Hysterectomy in Low Risk Cervical Cancer
  108. Public Health Initiative on Alcohol Flushing
  109. Virtual Exercise on Elderly Breast Cancer Survivors
  110. Prediction of Radiotherapy Efficacy in Patients With Triple-negative Breast Cancer
  111. Patient Navigation for Colorectal Cancer Screening
  112. M-PART in Head and Neck Cancer Patients Treated With KeraStat Cream for Acute Radiation Dermatitis
  113. The Effect of Breast Cancer Prevention Journey Program
  114. Personalised Health Recommendations to the General Population Through an Integrated AI Guided
  115. Implementation and Evaluation of an Evidence-Based, Multilevel Lifestyle Intervention for Underserved and Rural Populations in South Texas
  116. Comparing Cosmetic Outcomes: Endoscopic vs. Conventional Craniotomy for Frontal Skull Base Lesions
  117. Benefit of Spectral Information in Patients Suspected for Lung Cancer
  118. Autologous Tumor-Infiltrating Lymphocyte (GT307 Injection ) for Treatment of Patients With Solid Tumours
  119. Comprehensive Geriatric Assessment (Tests) for Bladder Cancer Participants Undergoing Radical Cystectomy
  120. Pre-incisional Wound INfiltration and Hypogastric PLEXus Block Using Ropivacaine in Laparoscopic Myomectomy
  121. Circulating Tumor DNA Based Adjuvant Chemotherapy in Stage II Colon Cancer Patients: the MEDOCC-CrEATE Trial
  122. Remote Exercise and Nutritional Prehabilitation for Pancreatic Cancer
  123. Early Detection of Esophageal Squamous Cancer With the Capsule Sponge Device
  124. Wecare Study in Gastric Cancer Survivors
  125. MWA vs RFA for the Treatment of Moderate-sized Benign Thyroid Nodules
  126. Recombinant Human Thyroid Stimulating Hormone for Radioiodine 131I Treatment
  127. Outpatient Pulmonary Rehabilitation in Non-small-cell Lung Cancer Receiving Immunotherapy
  128. Pelvic Floor Dysfunction and Aerobic Training in Gynecological Cancer
  129. Modulated Mid-frequency Whole-body Electromyostimulation and Nutritional Therapy in Gastrointestinal Cancer Patients
  130. NBI for Early Diagnosis of OPMD/OSCC
  131. Mapping Patient Decision-making in Thyroid Cancer
  132. THRIVE Well Cancer FDTN/Exercise_Creatine Supplementation
  133. Sugammadex v.s. Neostigmine/Glycopyrrolate
  134. CHEmotherapy and Cognitive Deterioration in Patients With Operable Breast Cancer: Impact of Cognitive Rehabilitation (CHEMOFOG)
  135. Yoga-Based Breathing Exercise, Colorectal Cancer Surgery
  136. FAPI and FDG PET/MRI in Diagnosis and Therapy Prediction of Bladder Cancer
  137. Comparing Bp-MRI and Mp-MRI for Prostate Cancer Screening Accuracy
  139. The Preventive Effect of Chemotherapy-induced Hand-foot Syndrome
  140. Efficacy and Safety of HILOTERMΒ® Device for the Prevention of Peripheral Neuropathy
  141. Prospective Study for Endometrial Carcinoma and Hyperplasia in Childbearing-age Women
  142. Somatic Acupressure for Symptom Cluster Management in Breast Cancer Survivors
  143. Fasting Mimicking Diet for Reducing Immune Related Adverse Events for Cancer Patients on Immune Checkpoint Inhibitors, FMD-ICI Trial
  144. Evaluation of Combined Modality Protons and Hepatic Transplantation for Hilar Cholangiocarcinoma
  145. Developing Inclusive Support and Intervention for Spanish-speaking LatinΓ© Prostate Cancer Survivors
  146. Evaluating Procedures for a Study of the AYA Survivors Coping and Emotional Needs Toolkit
  147. Mitigating Toxicity by Electronic Health Portal-mediated Interactive Monitoring of Patient-reported Side Effects
  148. Timing of Surgery After Neoadjuvant Chemotherapy for Advanced Ovarian Cancer
  149. Glioma Intraoperative MicroElectroCorticoGraphy
  150. Enhancing Access to Supportive Services for Women of Color With Metastatic Breast Cancer
  151. Identification and Characterization of Circulating Tumor Cells Before and After Treatment (Surgery and Radiotherapy) in a Cohort of Patients Treated for Resectable Stage I-III Merkel Cell Carcinoma
  152. Low-dose Chemotherapy Under Hypoglycaemia for the Treatment of Relapsed Refractory Advanced Solid Tumours
  153. Effects of a Strength Physical Exercise Program in Colorectal Cancer Patients Undergoing Chemotherapy Treatment
  154. Comparison of Erector Spinae Plane Block and Serratus Posterior Superior Intercostal Plane Block
  155. Physical Activity Centers Empowerment
  156. VitalTraq for the Detection of CRS
  157. Effect of Preoperative Exercise on the Prevention of Secondary Lymphedema in Breast Cancer Patients
  158. Decreasing Chemotherapy Induced Distress Using Immersive Virtual Reality in Patients With Cancer
  159. ColoSealβ„Ά ICD System Safety and Feasibility Study
  160. Combined Anti-IL6R and Anticoagulation Therapy in Advanced NPC Patients
  161. 3D Printed Custom Applicators for HDR BT (DISCO)
  162. The Long Term Effect of MRI Before Radical Prostatectomy.
  163. A Culturally-Tailored Mobile Health and Social Media Physical Activity Intervention for Improving Physical Activity in Hispanic or Latino/Latina Adolescent and Young Adult Childhood Cancer Survivors, Walking Juntos Study
  164. A Prospective, Randomized, Open, Parallel-controlled, Superior-efficacy Clinical Study of Radical Sigmoidectomy for Sigmoid Cancer Versus Radical Sigmoidectomy Combined With Indocyanine Green Fluorescence Imaging Lymphatic Tracing Dissection in the Treatment of Sigmoid Cancer
  165. Posterior Extra-fascial RARP in Intermediate or High Risk Prostate Cancer
  166. Targeted Microwave Tissue Coagulation for Prostate Cancer
  167. Goals of Care Discussion for Patients With Advanced Lung and Gastrointestinal Cancer in the Emergency Department of a Comprehensive Cancer Center
  168. Investigating the Role of Adjuvant Proton Beam Therapy in Patients With Parotid Carcinoma
  169. Comparison of the Efficacy of Cryotherapy Combined With Compression in Preventing Neuropathy
  170. The Clinical Efficacy and Safety of Intratumoral Injection of Chemotherapy for Advanced Solid Tumors
  171. Can Needle Size Improve Cancer Detection Rate of Transperineal MRI Target Prostate Biopsy Without Affecting Side Effects?
  172. WASPE Sleep Adjustment for Children Aged 0-4 Years Undergoing Radiation Therapy
  173. Preoperative Oral Midazolam to Postoperative Pain Relief in Sleep Disturbance or Anxiety Patients With Colorectal Cancer
  174. Remotely Monitored Exercise Interventions in Patients With mCSPC Undergoing ADT (Prostate 006)
  175. Preoperative PSMA PET/CT as Triage for ePLND in Patients Scheduled for RALP (PrePSMA)
  176. HPV Self-sampling for Underscreened Latinas
  177. A Prospective Interventional Study on Early Screening for Lung Cancer Using Liquid Biopsy
  178. Mannitol Versus Nitroglycerin for Kidney Injury Prevention in Robotic-assisted Radical Prostatectomy or Cystectomy
  179. Opioid-free Anaesthesia in Breast Cancer Surgery
  180. Little Cigar and Cigarillo Warnings for Youth
  181. VIBE - Virtual Image Guided Brachytherapy Emulation for Locally Advanced Cervical Cancer (LACC)
  182. Exercise as Intervention in Chronic Lymphocytic Leukemia
  183. Interprofessional Mindfulness Practices Advancing Cancer Teamwork
  184. Supporting the National Expansion of HPV-based Cervical Cancer Screening in Tanzania Among Women Living With HIV
  185. Colorectal Cancer Screening Intervention Study
  186. Electronic Symptom Monitoring Program for Triggered Palliative Referrals in Patients With Thoracic Cancer
  187. Perineal Massage in Women With Gynecological Cancer
  188. Mobile Application to Improve Health-Related Outcomes in Patients With Advanced Lung Cancer
  189. A Randomised Controlled Trial to Evaluate the Impact of Complement Theory's Live 1:1 Exercise Coaching and Personalised Digital Application on Cancer Survivors' Cost of Care
  190. Study to Compare Two Partial Nephrectomy Techniques for Renal Tumors: Robot-assisted vs Videolaparoscopic
  191. Digital Storytelling in Symptom Management Pediatric Oncology
  192. TPF Concurrent Chemo-radiotherapy Plus Immunotherapy for Local Advanced Esophageal Squamous Cell Carcinoma
  193. The Effect of Sujok Therapy on Patient Comfort, Pain Intensity, and Anxiety Level in Cancer Patients With Port Catheter Placement
  194. Anti-Inflammatory Lifestyle Intervention for Emerging Adult Cancer Survivors
  195. Clinical Research on the Application of Single-channel Uterine Fibroid Morcellation System in Laparoscopic Myomectomy
  196. Using Text Messages to Improve Oral Chemotherapy for Adolescents and Young Adults With Acute Lymphoblastic Leukemia
  197. History of Polycystic Ovary Syndrome in First-degree Relatives


The above Clinical Trial information has been retrieved from ClinicalTrials.gov